SHARPR

Systematic High-resolution Activation and Repression Profiling with Reporter-tiling

Example of Sharpr tiling.

SHARPR is software for analyzing Massively Parallel Reporter Assay tiling designs allowing mapping at high resolution activating and repressive nucleotides across thousands of regulatory regions.

Access the main SHARPR website

Citation:
Ernst J, Melnikov A, Zhang X, Wang L, Rogov P, Mikkelsen T, Kellis M.
Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions.
Nature Biotechnology, 34:1180-1190, 2016.